Semaglutide Ozempic® / Wegovy®
The SHIKARI® Semaglutide portfolio provides quantitative anti-semaglutide antibody analysis with an IFU-defined confirmation workflow.
Why Semaglutide is relevant to biological-drug monitoring research
Semaglutide has clinically important target biology, indication-specific dosing and measurable systemic exposure, making drug concentration and immunogenicity relevant research variables. Scientific source ↗ · EMA source ↗
Molecular Target & Structure
Semaglutide is a long-acting GLP-1 receptor agonist peptide analogue that enhances glucose-dependent insulin secretion, suppresses glucagon and slows gastric emptying. Source ↗
Approved Indications
For the Ozempic®-family product context relevant to this page, EMA authorisation is for adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise, used alone or with other glucose-lowering medicines according to the label. EMA source ↗
Weekly Steady-State Exposure
FDA pharmacokinetic data show approximately dose-proportional steady-state serum concentrations under weekly subcutaneous dosing:
Regulatory exposure values are regimen- and population-specific and are not therapeutic targets. Values vary with dose, timing, formulation and study population. This page is for RUO product information and does not provide clinical guidance.
One verified Semaglutide research assay
Quantitative ELISA for anti-semaglutide antibodies with an assay-specific confirmation workflow.
Verified Specifications at a Glance
| Kit | REF | Mode | Analyte | Sample | Volume | Time | Analytical output | Tests | Shelf life | Storage | Shipping |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SHIKARI® S-ATSEM | SEM-QNS-OZE | Quantitative | Anti-semaglutide antibodies | Human serum / plasma | 5 µL | 140 min | LOD 5 ng/mL; LOQ 1.56 µg/mL | 96 | 6 months | 2–8°C | 10–30°C |
Analytical specifications are summarised from the current controlled IFUs and exact official product records. Standard curves are official illustrative images and must not be used for sample quantification. Follow the link on each assay card for the corresponding product record on matriksbiotek.com.
Match the assay to the research question
Semaglutide Literature and Product-Use Records
Planning a Semaglutide research study?
Matrix Biotek can help identify the appropriate Semaglutide assay and prepare regional quotation and delivery information.