The Comprehensive Handbook on Biological Drug Monitoring
A four-chapter scientific resource on biological-drug monitoring, immunogenicity and related research applications, authored by Prof. Haluk Ataoglu, MD, PhD.
Four Comprehensive Chapters
Trough Levels & Anti-Drug Antibodies
The clinical and pharmacological foundation: why measure trough levels, how immunogenicity affects exposure, and the relationship between drug levels and clinical outcomes.
Anti-Idiotype Antibodies
Specific anti-idiotype antibodies as the foundation for high-precision drug-level assays. The biology, the production, and the clinical application of anti-idiotype-based ELISA platforms.
T-CAP NAb Assays
Target Capture Neutralising Antibody assays — the next generation of immunogenicity testing. How they work, why they matter, and how they distinguish neutralising from non-neutralising ADAs.
Patient Case Studies
Clinical case studies illustrating how biotherapy monitoring guides real-world treatment decisions — from IBD to oncology and beyond. Pattern recognition for the practising clinician.
Drawing on 23 years as Professor of Clinical Microbiology at Ankara University Faculty of Medicine and more than two decades of biotechnology entrepreneurship, this handbook is intended as an educational resource for researchers and laboratory professionals.
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