Filgrastim Neupogen® / Fraven®
The SHIKARI® Filgrastim portfolio provides quantitative anti-filgrastim antibody analysis with an IFU-defined confirmation workflow.
Why Filgrastim is relevant to biological-drug monitoring research
Filgrastim has clinically important target biology, indication-specific dosing and measurable systemic exposure, making drug concentration and immunogenicity relevant research variables. Scientific source ↗ · EMA source ↗
Molecular Target & Structure
Filgrastim is recombinant human granulocyte colony-stimulating factor (G-CSF) that activates the G-CSF receptor and stimulates production and maturation of neutrophils. Source ↗
Approved Indications
Authorised uses include reduction of chemotherapy-associated neutropenia, mobilisation of peripheral blood progenitor cells, severe chronic neutropenia and persistent neutropenia in advanced HIV infection in defined settings. EMA source ↗
Dose-Dependent Serum Exposure
Regulatory pharmacokinetic data demonstrate dose-dependent peak serum concentrations after subcutaneous administration:
Regulatory exposure values are regimen- and population-specific and are not therapeutic targets. Values vary with dose, timing, formulation and study population. This page is for RUO product information and does not provide clinical guidance.
One verified Filgrastim research assay
Quantitative ELISA for anti-filgrastim antibodies with an assay-specific confirmation workflow.
Verified Specifications at a Glance
| Kit | REF | Mode | Analyte | Sample | Volume | Time | Analytical output | Tests | Shelf life | Storage | Shipping |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SHIKARI® Q-AFA | FIL-QNS-FRA | Quantitative | Anti-filgrastim antibodies | Human serum / plasma | 10 µL | 140 min | LOD 2 ng/mL; LOQ 3.125 ng/mL | 96 | 1 year | 2–8°C | 10–30°C |
Analytical specifications are summarised from the current controlled IFUs and exact official product records. Standard curves are official illustrative images and must not be used for sample quantification. Follow the link on each assay card for the corresponding product record on matriksbiotek.com.
Match the assay to the research question
Filgrastim Literature and Product-Use Records
Planning a Filgrastim research study?
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